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Why did the healthcare provider change the prescription to a lipid-soluble drug for a client with meningitis?

  1. Lipid-soluble drugs are more effective because they are excreted at a lower rate

  2. Lipid-soluble drugs are more effective in treating the client's illness

  3. Lipid-soluble drugs are better because they have fewer side effects

  4. Lipid-soluble medications are better because of protein binding

The correct answer is: Lipid-soluble drugs are more effective because they are excreted at a lower rate

The healthcare provider changed the prescription to a lipid-soluble drug for a client with meningitis because lipid-soluble drugs are more effective in this case due to their ability to cross the blood-brain barrier easily. This is crucial for treating infections within the central nervous system, such as meningitis. Lipid-soluble drugs have a higher affinity for fatty tissues, which allows them to penetrate the blood-brain barrier more effectively compared to water-soluble drugs. This enhanced ability to reach the site of infection in the CNS makes lipid-soluble drugs a preferred choice for treating meningitis.